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Clin Chem Lab Med2013;51:633-7

Following transplantation, these cells must survive a hostile degenerative microenvironment characterized by nutrient deficiency, acidity, and inflammatory cytokines, which may induce cell death (e.g., pyroptosis) and further compromise their viability and function [36]

albicans were co-infected, a thicker, denser biofilm with stronger tolerance to harmful stresses was formed on root canal dentin and glass slides, which can increase bone resorption of osteoclasts, inhibit the bone formation of osteoblasts, upregulate inflammatory cytokines such as IL-6 and TNF-, and ultimately increase the severity of dental pulp diseases

So yeah, talk to your doctor first