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The animals had the access to food and water ad libido but the daily intake of the chow was controlled

These findings reveal that HSC aging is a driver of aging-associated inflammation through maladaptive trained immunity and broaden the possible clinical applications of targeting HSCs from hematological diseases to include countering aging-associated physiological decline and improving healthspan

Pre-treatment screen: LFT, RFT, G6PD assay, fasting glucose

Their adding-value applications through advanced biotechnological methods in agricultural, food processing, and medical fields not only mitigate the environmental pressure brought by their discard but also bring new opportunities for the progress of agriculture, food processing, and medicine