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Higher CD34 expression was noted in non-cirrhotic vs cirrhotic PC regions (median: 2.27 vs 1.45, p =0.046) and higher VEGF expression was observed in middle-stage (IF 3-4) vs cirrhotic PC zones (95.77 vs 41.64, p =0.018)

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Giustarini D, Rossi R, Milzani A, Colombo R, Dalle-Donne I: S-glutathionylation: from redox regulation of protein functions to human diseases

For multi-arm or longitudinal studies, researchers can correlate batch-specific variation with endpoint variation, something that is awkward to reconcile when reconstituting from unlabelled lyophilised vials across multiple sessions, where each reconstitution introduces fresh variables