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For comparison, FDA-approved anti-obesity medications like semaglutide 2.4 mg (Wegovy) have cardiovascular outcomes data from the SELECT trial (N=17,604, median follow-up 39.8 months), which demonstrated a 20% reduction in major adverse cardiovascular events [6]

(PubMed) Evans JL, Heymann CJ, Goldfine ID, Gavin LA

Clinical trials of semaglutide showed participants lost 1022% of their body weight over 68 weeks, depending on the dose and individual metabolic response

In a clinical setting, a physician evaluates whether these peptides are appropriate for patients experiencing metabolic concerns such as impaired fat loss, reduced energy, or decreased metabolic efficiency