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Chronic inflammation, in turn, enhances the expression of pro-fibrotic factors via the activation of pathways like NF-B, damaging atrial intercellular junction proteins (e.g., Cx40 and Cx43) and affecting electrical signal transmission in the myocardium (Karam et al., 2017)

enterica serovar Typhimurium, invasive enteric pathogen, represses serine synthesis in macrophages in vitro, via a type III secretion system effector protein called SopE2, leading to the accumulation of 2-PG, 3-PG and phosphoenolpyruvate, which serve as carbon sources 141 (Fig

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(1969) Superoxide dismutase