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FIGURE 6 GPX4GSHcysteine system Ferroptosis was first reported to induce iron-dependent cell death via the small molecules erastin and 1S,3R-RSL3 (RSL3), a classical feature of ferroptosis is that it is independent of Caspase activation after erastin and RSL3 treatment (Wang et al., 2016)

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References: Benowitz NL (2024): Antihypertensive Agents (Chapter 11)

Similarly, the variant of Cr FAP65AH2 did not show any interaction (Fig