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ROS-mediated signaling is involved in multiple processes, such as cell growth [14, 15], stem cell renewal [16, 17], tumorigenesis [8, 14, 17], cell death [14, 15], cell senescence [15, 17], cell migration [16], oxygen sensing [15], angiogenesis [15], circadian rhythm maintenance [16], and immune responses [8, 15]

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The main objective of this review is to synthesize the physiological responses and adaptive mechanisms of amphibians and reptiles under multiple interacting environmental stressors