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Although the heterologeous expression of an insect steroid receptor in CHO-K1 cells differs largely from the situation found in LNCaP cells that express high levels of intracellular AR under physiological conditions the present data suggest that there are cell specific differences in the sensitivity of cells towards NO-treatment

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PLC- and its related signals can promote or inhibit the occurrence and development of cancer by affecting the growth, differentiation and metastasis of cells, while targeted intervention of PLC-1-PI3K-AKT, PLC-2/CD133, CXCR2-NHERF1-PLC-3, Gq-PLC-4-PKC-MAPK and so on can provide new strategies for the precise prevention and treatment of malignant tumors

[DOI] [PubMed] [Google Scholar] 221.Kretzschmar M, Muller D