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It is important to note that the efficacy of intravenous immunoglobulin therapy for sepsis has been controversial, but targeting the pathway that inhibits the immune activation response to neuroinflammation is hoped to lead the way from the very beginning to the development of SAE and is likely turn out to be a brand-new strategy in the treatment of SAE

Excessive caffeine in coffee, tea, or energy drinks: It can also increase oxidative activity in the body, which reduces antioxidants action

doi: 10.1186/s12974-015-0329-1 298 RivesA.MeierJ.SercuT.GoyalS.LinZ.LiuJ.et al