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Although dabigatran is mainly used in patients with cardiovascular disease, atrial fibrillation, or stroke, and the pharmacokinetic and pharmacodynamic properties of the healthy population differ from those of patients, the pharmacokinetic parameters of healthy subjects are more stable and can more clearly reflect the absorption, distribution, metabolism, and excretion characteristics of the drug, thus providing reliable baseline data for subsequent patient studies to validate the efficacy and safety of dabigatran in specific disease states

In the NDD-CKD group, adverse events (dialysis access thrombosis, infection, hyperkalemia, and seizures) occurred more frequently in the HIF-PHI group compared with the placebo group

He then used the proceeds from auctioning off his own game-worn sneakers last season to help pay for the college educations of two students