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Elevated MMP levels correlate with enhanced basement membrane penetration and metastatic dissemination, while the coordinated regulation of EV-mediated signaling and miRNA networks provides mechanistic evidence for LMF-driven metastatic progression specifically in malignant cells

Platelet-rich plasma (PRP) is autologous (no steroid, no exogenous drug) and is increasingly supported by randomised trials and meta-analyses across common indications (knee OA, rotator cuff disease, lateral epicondylitis), with fewer systemic risks than corticosteroid injections