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The PDTD, released in 2008, includes approximately 1100 protein entries with 3D structures, sourced from literature and various online repositories (e.g., Therapeutic Target Database (TTD), DrugBank, and Thomson Pharma), covering 830 known or potential drug targets [130]

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Interestingly, noncovalent Ub or polyUb binding attenuated UBQLN2 phase separation 127

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