a locally activatable sensor for robust quantification of organellar glutathione

a locally activatable sensor for robust quantification of organellar glutathione Systemic cyst(e)inase administration induces ferroptosis and synergizes with temozolomide in glioblastoma RCSB PDB - 7ZBB: HaloTag

Name: a locally activatable sensor for robust quantification of organellar glutathione Systemic cyst(e)inase administration induces ferroptosis and synergizes with temozolomide in glioblastoma RCSB PDB - 7ZBB: HaloTag
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SKU: 64070241687
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RCSB PDB 7ZBB: HaloTag with TRaQ G ctrl ligand Glutathione driven redox decisions in cell survival and death Highly sensitive quantitative detection of glutathione based on a fluorescence colorimetric dual signal recognition strategy ScienceDirect Characterization of the glutathione redox state in the Golgi apparatus ScienceDirect

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Description

Upstream signals are sensed by GSH and, depending on the GSH buffering capacity, transmitted into a downstream response

The arrow in the diagram to the right shows where the glutathione is located in the liposome.* Liposomes penetrate mucosal tissues allowing for rapid release into the blood stream