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For instance, during the early phase of muscle regeneration, pro-inflammatory macrophages and T cells were shown to release pro-inflammatory cytokines, such as TNF-, IL-1, and IL-6, promoting myoblasts proliferation 7,8 , whereas anti-inflammatory macrophages and Tregs involved in the later phase of acute injury secrete cytokines/growth factors promoting myoblasts differentiation and fusion (e.g., IL-4, IGF-1) 9,10

Consulting a doctor can help determine the most suitable option based on your skin type and condition