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2.2 Salinity, GSH and BSO treatment Healthy thalli were cultured in mediums of natural seawater diluted with 0% (v:v), 50%, and 100% sterilized freshwater, i.e., salinity of ~ 30 psu, 15 psu, 0 psu, respectively, at 14C, 40 mol photons m 2 s 1 , pH 8.0, 12 h:12 h L: D

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Whilst a single dose of 1015 g is likely to result in severe liver damage 3 , prolonged exposure to acetaminophen has been shown to result in autoprotection in some patients, such that daily doses even in excess of 10 g have apparently little adverse effect

However, we previously reported that IBS is associated with a marked increase in IFN- gene and IFN- protein expression in the colonic mucosa (211), a finding also supported by evidence of increased IFN- release in the lumen (222)