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Heavy metal toxicity: Common causes The prominent causes of Heavy Metal Toxicity are environmental sources that may be based in the food that is consumed or the water that is being drunk or even over exposure to industrial metals and chemicals

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Figure 1 Regulatory mechanism (Figure 1): The essence of ferroptosis lies in the depletion of glutathione (GSH) and the decline in the activity of glutathione peroxidase (GPX4), which leads to a reduction in the amount of glutathione reductase catalyzed by GPX4 and excessive accumulation of lipid peroxides (10)