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It is well known that traditional Chinese medicine functions through synergistic effects of multiple components on multiple targets, and that the active substances may be a group of components with similar structures

Because the brain has high energy demands, limited energy reserves, and an abundance of phospholipids that serve as substrates for oxidative damage, it is especially vulnerable to disruptions in iron metabolism and the resulting oxidative stress (Altahrawi et al., 2025)

Notably, the results of these studies above showed that the inhibitory concentrations of LBP, APS, RGP and POL were within the broad dosage ranges of 50 g/mL to 100 mg/mL in various cancer cells for 48 h, especially APS and LBP, exhibiting various therapeutic effects

However, surgery has several drawbacks, including economic burdens and complications such as inflammation, xerophthalmia, macular edema and posterior capsular opacification