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Summary: Vitamin B12 is a single nutrient targeting specific deficiency or high-risk groups, whilst B complex contains all eight B vitamins for broader nutritional support

Despite the obvious consequences of the functional B2 deficiency in the metabolism of B12, the majority of authors do not seem cognizant of this (Obeid etal, 2015), and seem to believe that B12 deficiency only occurs due to low intake of the vitamin, rather than ineffective processing, and are unaware of the phenomenon of Paradoxical B12 deficiency

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Evaluating peptide interactions and biological responses remains a key component of high-quality research design