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Changes in gut microbiota, including families like Pasteurellaceae and genera such as Haemophilus, correlated with behavioral improvements, indicating a potential microbiome-mediated mechanism

Chronic neuroinflammation, the response to sustained and widespread stimuli, typically occurs due to either disease (e.g., Alzheimer's and multiple sclerosis) or persistent infection by viruses (Olson et al., 2001

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In addition, several studies demonstrated that injected mesenchymal stem cells (MSCs) become undetectable in a short period due to premature death after implantation (Vadal et al., 2012