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Such insights are critically important to develop peptides, peptidomimetics or small molecules that specifically and effectively disrupt AR-coregulator interactions that control aggressive CaP behavior

After blocked with 5% BSA, the membranes were incubated with specific primary antibodies overnight at 4 C

Molecular mechanisms underlying the anti-aging effect of NAD+ Cross-talk with pathways inside the nucleus As mentioned earlier, the low level of energy synthesis and unbalanced oxidative stress are important initial links, which lead to the increased expression of pre-apoptotic signals and inflammatory factors

(2025) 12:e2411479