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Recordings were conducted during the first 5 min after establishment of the wholecell condition

Respective simulations indicated that predictions based on a compartmental approach described the observed oral C/t with reasonable accuracy (Figure S4)

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see Background section and Example 1 discussion) of about 100-150 nM/10 5 WBC, or about 127.8 19.8 nM/10 5 WBC, or about 127.8 nM/10 5 WBC, as measured by the Tietze method, for example