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In vitro experiments demonstrated that cancer-associated adipocytes upregulate the hexosamine biosynthetic pathway (HBP), leading to O-GlcNAcylation and stabilization of the YAP protein

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Collectively, these findings underscore the complexity of treating stress and sleep disorders, highlighting the variable effectiveness of treatments like GABA, DSIP-CBBBP, DSIP, and CBBBP alone in modulating key biochemical biomarkers