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Conclusion Randomized controlled trials (RCTs) provide the regulatory gold standard for establishing efficacy, yet their strict eligibility criteria often limit generalizability to real-world patient populations

Won et al

IV daratumumab was demonstrated in RRMM patients for monotherapy in the Phase III COLUMBA trial ( 3 prior lines) and in standard combination regimens in the Phase II PLEIADES trial ( 1 prior lines) [14]

The evidence suggests that it may offer some benefits in reducing melanin production and promoting a lighter complexion, particularly in certain individuals