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If you're storing reconstituted solution at room temperature for weeks, or using it past 14 days, or exposing vials to direct light during storage, you're injecting degraded peptide fragments that retain minimal biological activity

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CBS 516525 , where the protein can respond to both ligand binding and conformational changes, also presented two events, though this construct is dimeric and will likely not form a putative second SAM site at a higher order oligomeric interface (Supplementary Figs