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However, other forms of HH, known as non-HFE haemochromatosis, also share the trait of having low plasma hepatic phospholipid levels that are out of proportion to the bodys iron levels

We reasoned that if we could genetically modify lines to produce gametes of only one or the other sex, these could be engineered further, such that in a genetic cross, each sex would separately deliver either a Cas9 endonuclease or a guide RNA to the zygote and cause a double-strand break in a target gene