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Therapeutic roles of curcumin: lessons learned from clinical trials

In Mtb, pharmacological inhibition of PyrG could interfere with DNA/RNA biosynthesis, and other nucleotide-dependent metabolic processes, such as the biosynthesis of fatty acids, carbohydrates, amino acids, and cAMP or c-di-AMP [295]

6 Orthopaedics Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan, Peoples Republic of China *These authors contributed equally to this work Correspondence: Yingze Zhang