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In proximal renal tubular epithelial cells (TECs), autophagy inhibition, such as chloroquine or ATG7 depletion, reduces fibrosis, suggesting that autophagy may promote injury (Nam et al., 2019)

The above signalling pathways triggers inflammatory cascade leading to the production of numerous inflammatory cytokines, pro-fibrotic molecules, Interleukin (IL)-1, IL-6, tumour necrosis factor (TNF-) Monocyte Chemoattractant Protein-1 (MCP-1), Connective Tissue Growth Factor (CTGF), Platelet-Derived Growth Factor (PDGF) and Vascular Endothelial Growth Factor (VEGF) in the membrane (Balzer, 2020

It is a naturally extracted formula that has zero side effects

This finely regulated crosstalk ensures a balance between the supply and demand of carnitine in different physiological and pathological states, thus supporting the health and function of the whole organism