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Natriuretic Peptides Atrial Natriuretic Peptide (ANP) and B-type natriuretic peptide (BNP), the main natriuresis hormones, are synthesized in cardiac tissue in response to stretching that occurs with increases in blood volume and function to decrease extracellular fluid volume and increase renal sodium excretion (108)

Break periods between cycles Between AOD-9604 cycles, a break period allows receptor sensitivity to restore and prevents potential adaptation that could reduce effectiveness in future cycles

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