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It seems possible that oxidation of these thiols to disulfides, under a mechanism of oxidative stress, would increase the affinity of SARS-CoV and SARS-CoV-2 S proteins for the ACE2 receptor, and therefore, increase the severity of COVID-19 infection [30, 60]

12) by the comparison of isotopologue similarity, relevance to reference reactions, and interpretation of MS/MS spectra

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Amyotrophic lateral sclerosis ALS is a neurodegenerative disease where the degeneration of motor neurons dominates the clinical presentation and the course of the disease, which is fatal within a few years from onset