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This review provides a comprehensive summary of the current status of iron chelation therapy for CNS disorders with a focus on pharmacokinetics, efficacy, and translational potential of IN administration

Vitamin D signaling system genes, which has large CpG islands in their promoter regions and is prone to be regulated by DNA methylation and therefore can be silenced by de novo methylation 32,33,34,35

It is worth emphasizing that clinical data in the scientific literature remain limited

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