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Microglia in a chronic inflammatory state can also promote the aggregation of -syn to form Lewy bodies, which are mainly distributed in neurons throughout the brain

Aliya S (2021) Targeting key transcription factors in hepatocellular carcinoma

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Violin plots of senescence-associated gene expression (cell cycle arrest, DDR, SASP) in endothelial cell subpopulations indicated that the transcriptomic profile of ECs in the Mid-old+HHcy group exhibited pronounced senescent alterations (Figure 2J)