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EP-7041, a small molecule FXI antagonist, has demonstrated safety and good tolerability in Phase 1 human studies (73)

Additionally, polyelectrolyte complexation can be used to encapsulate bioactive peptides or proteins during fabrication, typically utilizing heparin and PLL

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capsulatum and Blastomyces SOD3 have a conserved predicted signal peptide and a glycophosphatidyl inositol (GPI) anchor (Fig 1A) [15, 28], which could allow the cell to excrete the protein and to associate with the cell surface, suggesting its role as an extracellular Sod