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It can increase strength, endurance, cell volumization and power output, and has been shown to boost anabolic hormones like IGF-1 while reducing muscle breakdown

Bartels, D

Physical exercise and particular nutrients, including CIT and leucine, have demonstrated efficacy in upregulating the signaling pathways of PGC-1, SIRT1, and AMPK, thereby facilitating mitochondrial turnover and alleviating oxidative stress (74)

To bridge the gap between preclinical findings and clinical application, future research on forskolin and carotenoids should prioritize human safety and tolerability to establish optimal dosing and formulation