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Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose

While preclinical findings are encouraging, human clinical evidence remains limited , and the compound should be viewed as a research-stage metabolic therapy rather than an established treatment for obesity or weight management

Fix: Commit to minimum 8 weeks, preferably 12 weeks

Veterinarians may wish to default to chewable or palatable formulations when they are available or consider alternatives to oral medications when longer-lasting injectables are indicated and available to reduce pet owner anxiety and stress