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Another process, known as oxidative stress , may contribute to inflammation, damage to blood-vessel walls, oxidation of cholesterol particles, and the development of atherosclerosis

Mol Med Rep 2019;19:10408

In addition to hormone metabolism, selenium-dependent enzymes provide antioxidant protection (130)

Enzymatic antioxidants convert the ROS to less reactive compounds, such as water and oxygen, while non-enzymatic antioxidants donate an electron to quench the ROS