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Its relevance to exercise and aging has recently attracted attention, as glycine availability declines with age, potentially contributing to impaired muscle repair, reduced metabolic flexibility, and increased oxidative stress ( Clinical studies examining direct supplementation are limited, but glycine's involvement in glutathione synthesis suggests a protective effect against exercise-induced oxidative stress

It will show results but gradually

20 KumarK.KumarS.DattaK.FornaceA

The cultured SGN explants from WT or gpx1 / mice were exposed to peroxynitrite with or without ebselen pretreatment, and the expression changes of 4-HNE were examined to evaluate the oxidative stress level in SGNs (Figure 5A)