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Myeloid-derived suppressor cells (MDSCs), immunosuppressive cells activated during tumor progression, can inhibit specific immune responses and contribute to tumor resistance to immunotherapy [148]

TMEM206 plays a role in mediating acid-induced cell death as well as cell proliferation and migration, and its regulation is dependent on p53 through a p21-dependent mechanism (346)

Additionally, minimizing the exposure and drying of the intestinal surface, as well as removing residual tissue fragments, can reduce the risk of adhesion formation (94)

Both vaccines and wild-type strains indicated similar proliferative responses to PPDa antigen and there was no significant difference between treatment groups at all three time points