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Its popularity stems from promising preclinical research and widespread anecdotal reports about its recovery and healing properties

Understanding the root cause is essential for effective treatment and long-term management

It has been proved that Fe 2+ , erastin and RAS-selective lethal 3 (RSL3) can induce cardiomyocyte cell death (Kobayashi et al., 2018)

It has been observed that the thiol group of glutathionine is oxidized less readily than that of cysteine, due to the protection of the free amine of cysteine by glutamylation [75,27]