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Medications that reduce B12 absorption: Proton pump inhibitors (PPIs) such as omeprazole, lansoprazole, and esomeprazole are amongst the most commonly prescribed drugs in elderly populations

Based on the positive results from three Phase III studies, in 2012 FDA approved topiramate/phentermine extended-release as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in eligible adults

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Among its various functions, the role as immunomodulator in cellular immunity, especially in elevating the number of CD8+ cells and NK cells, attracts scientific interest