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[9] AOD 9604 and Joints Research suggests that AOD 9604 may influence arthritic joints in rabbits, and may have contributed to an improvement in pain perception and decreased movement disability

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Additional at-risk groups include: Vegans and strict vegetarians , who may have low dietary B12 intake People with autoimmune conditions , including pernicious anaemia or type 1 diabetes Individuals with gastrointestinal conditions such as Crohn's disease or coeliac disease, which impair nutrient absorption People who have undergone bariatric surgery , which can significantly reduce B12 absorption Long-term users of proton pump inhibitors (PPIs) or H2-receptor antagonists , which reduce gastric acid and impair B12 release from food Those with a family history of either pernicious anaemia or diabetes For these groups, simultaneous monitoring of B12 status and glycaemic markers is particularly important to avoid diagnostic errors

2014 Nov Jishui Zhang, Xueqian Ma, Yi Su, Lifang Wang, Shaomei Shang, Weihua Yue