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Glutathione Introduction Composition of Glutathione Mechanism of Action: How Glutathione Works Uses of Glutathione Off-Label Uses of Glutathione Dosage and Administration Guidelines Side Effects of Glutathione Interactions with Other Medications Contraindications and Warnings Special Considerations in Administration Handling and Storage of Glutathione Overdosage: Symptoms and Management Important Precautions and Careful Administration Introduction Glutathione, an antioxidant in the human body, comprises glutamine, cysteine, and glycine

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FIGURE 1 2 H 2 S inhibits hepatocellular carcinoma 2.1 Exogenous H 2 S inhibits hepatocellular carcinoma 2.1.1 Exogenous H 2 S inhibits hepatocellular carcinoma by blocking the STAT3 pathway The signal transducer and activator of transcription (STAT) protein is a potential cytoplasmic transcription factor, which includes seven members: STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6 ( 2 S) suppressed IL-6-induced STAT3 activation through effectively decreasing p-STAT3 levels by reducing JAK2 phosphorylation (an activator of STAT3) in HCC cells