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CMS will demand repayment of any unspent prepaid shared savings, as well as any outstanding balance of prepaid shared savings, at the end of each agreement period in which an ACO receives prepaid shared savings, as noted in the new 425.640(e)(3) and (g)(3)

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Smoking cessation, while beneficial for improving treatment outcomes, presents its own set of complexities, particularly in adjusting therapeutic regimens as enzymatic activity normalizes post-cessation

167,171,172 Management strategies focus on tight glycemic control to prevent further nerve damage, symptomatic treatment with analgesics for pain management, physical therapy to maintain muscle strength and prevent contractures, and surgical interventions for entrapment neuropathies when necessary