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HMWK is involved in these steps and is also converted to kinins, which can cause vasodilation, erythema, and pain

Anecdotal evidence points to reduced trunk fat and waist circumference after use

Mitochondrial respiration of human platelets in young adult and advanced ageseahorse or O2k

Over the following weeks most people notice steadier energy and fewer afternoon crashes first (weeks 12), then early fat loss around the midsection with workouts feeling more productive (weeks 24), then measurable body-fat reduction and better endurance and recovery (weeks 48), with metabolic markers like glucose and triglycerides often improving by week 8+