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10.1515/jbcpp-2011-0033 J

Additionally, Puerarin (40 M) treatment was found to decrease the expression of NF-B-associated inflammatory factors (IL-6 and IL-8) while increasing the levels of Nrf2 and its associated antioxidant genes (GSH, SOD, CAT), thereby mitigating inflammation and oxidative stress induced by H 2 O 2 (400 M) in BMECs (79)

Working in enclosed office buildings, using (necessary!) SPF creams, and covering the body with clothing all make it very difficult, if not impossible, to obtain adequate levels of vitamin D from sunlight

Antioxidants like selenium and vitamin E can attenuate oxidative stress and protect melanocytes from ferroptosis