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Yet, we noted that FUS-induced BBB opening combined with GSK-3 inhibitor delivery had an additive effect on plaques reduction efficiency reaching 39.6% reduction, compared to 15.1% with FUS-BBB opening alone and 22.6% with GSK-3 inhibitor administration alone (see Fig

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The difference between recurrent and primary scores was defined as an indicator of drug sensitivity: positive values signified drug resistance, while negative values reflected drug sensitivity