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Two to six times more ynfA gene expression than tolC gene expression was observed (Sarkar et al., 2015)

Avoid direct contact with the peptide or solvent using bare hands

This allowed for multivalent binding to the EGFR receptor, overexpressed on inflammatory breast cancer (IBC) cells, and ultimately enabled the delivery of the enzyme intracellularly

Thus, the dosage in individual cases was modulated to avoid the occurrence of specific clinical side effects or blood exam abnormalities (headache and insomnia, weight changes, age, neutropenia, alteration of liver function indices, hypercholesterolemia, gastrointestinal disturbances) by adjusting to maximal dosage without side effects, as required for off-label drug administration