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SKU: 67297147478
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Availability: InStock
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Description

The gut microbiota is responsible for the production of a wide array of compounds, each possessing the capacity to induce DNA damage either through direct or indirect mechanisms (Pleguezuelos-Manzano et al., 2020)

A second pathway requires betaine as a methyl donor for the methylation of homocysteine to form methionine

Preclinical studies show promise in targeting E3 ligases (MDM2, TRIM26) or DUBs (USP14, OTUB1) to destabilize critical radioresistance mediators like GPX4, HIF-1, and PARP1 [10, 56, 152]