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In conclusion, by using quantitative GBCA datasets from both mice and humans, we demonstrated that a deep learning model can, in principle, generate GBCA-equivalent information from a single structural MRI scan for the estimation of regional CBV, and we successfully applied our DeepContrast model to both an in-house aging dataset and a publicly available ADNI dataset from Alzheimer's patients and age-matched controls

Mohammadi EN, Louwies T, Pietra C, Northrup SR, Meerveld BG-V

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