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74 Paradoxically, RIPK3-knockout mice exhibited exacerbated hepatocyte steatosis and liver injury compared with wild-type mice that were fed HFD

Specifically, these substitutions occur at positions 2, 8, 15, and 27 of the native GHRH(1-29) sequence (sermorelin)

This study offers an explanation for the paradox of insulin resistance, in which insulin fails to suppress glucose production but continues to promote lipid synthesis