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Furthermore, the relative expression of NeuN fluorescence (fluorescence/area) in the ROT-induced group was 0.007, significantly lower than that in the NC group ( P = 2.0 \(\times 10\) 2 ), which increased to 0.013 and 0.018 after SP and MH treatment, respectively, significantly higher than in the ROT-induced group ( P = 1.8 \(\times 10\) 2 and 1.2 \(\times 10\) 2 , respectively) (Fig